I would bet that the data shows that these high-dose opioids are not really the problem. I suspect what is abused is the regular low dose opioids but I need to see the data. I’m not sure if this proposal helps or hurts the problem.
Groups representing public health officials and doctors banded together Thursday to petition the US Food and Drug Administration to take ultra-high-dosage opioid pills, tablets and nasal sprays off the market. When prescribed, these opioids equal more than 90 milligrams of morphine (MME) a day in potency.
These can include higher dosages of both fast-acting, immediate-release opioids as well as slow-acting, longer-release formulations of oxycodone, hydromorphone, morphine, oxymorphone, hydrocodone, methadone and fentanyl.
The petition specifically requests the removal of OxyContin 80mg, which when taken twice a day equals 240 MME in 24 hours, as well as the removal of oxycodone 30mg, typically taken four times a day for the equivalent of 180 MME daily. (more…)